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Leaf icon Living With GIST

Life with advanced GIST is a constant battle and treatments often stop working.

See why
Doctor icon Talk With Your Doctor

Topics to address with your GIST care team throughout your journey.

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See how Qinlock works to treat advanced GIST.

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GIST Keep Going: Alli's QINLOCK story

Watch Alli T., a patient with advanced GIST, share the difference QINLOCK has made in her life

ALLI: Whatever journey you’re on, you can’t lose hope. QINLOCK has been the hope for me.

[SUPER]

Alli T.
Real Patient with Advanced GIST

[SUPER]

QINLOCK® (ripretinib) presents:
GIST Keep Going

ALLI: I love road trips. We’re both pretty spontaneous. We stop and see different people along the way, and it’s just a nice getaway from the winter.

ALLI: But, we stopped coming to Florida the first three years after I was diagnosed.

[SUPER]

Tim T.
Alli’s husband

ALLI: Losing that independence was incredibly difficult.

TIM: I changed from being a companion to a GIST specialist.

ALLI: In nine years, I was on three different treatments, but the GIST progressed. The strongest sense of fear that I had was finding out the third treatment failed. That’s when you do have to look, you have to look death in the face.

TIM: QINLOCK was really sent to us, because we were at a point where nothing was working.

ALLI: It’s just been a life changer for me. Because it not only has been working, but I feel good on it.

Within the first month I did lose my hair. And my doctor told me to expect nausea. I’ve been pleasantly surprised that it’s been to a minimal degree with QINLOCK, but I still have it.

ALLI: My first scan after starting QINLOCK was the typical three month scan. I went to meet with the doctor and he came in and he didn’t hesitate. He just said, “Good news.” I don’t really know how to explain that emotion when you’re told, like, you still might have some life.

TIM: We both just cried. I mean, uh, you know you, you get a new day.

ALLI: Living with cancer ten years, and you feel like there’s no hope. But, there was and it was right down the road. What if I had given up?

TIM: A bend in the road is not the end of the road, unless you fail to make the turn. And we had to make the turn.

ALLI: Don’t look at all the negatives. Through the whole process, you have to find hope.

[ENDING SUPERS]

Your journey. Your reasons.

[LOGO]

GIST Keep Going at QINLOCK.com

Handshake icon Care Partner Corner

As care partners to loved ones with GIST, you need support and places to ask for help too. And that’s ok. Self-care helps you stay strong so you can keep helping your loved one.

START HERE
 
Learn more about Living with GIST

Insurance help

Trying to understand your insurance can be a big challenge. Deciphera AccessPoint™ is here to help you make sense of it and find out what help is available.

VISIT DECIPHERA ACCESSPOINT

Important Safety Information

Qinlock may cause serious side effects, including:

A skin problem called palmar‑plantar erythrodysesthesia syndrome. Skin problems are common and sometimes can be severe. Tell your healthcare provider right away if you develop redness, pain, blisters, bleeding, or swelling on the palms of your hands or soles of your feet, or severe rash during treatment with Qinlock.

New skin cancers. Qinlock may cause skin cancers called cutaneous squamous cell carcinoma, keratoacanthoma, or melanoma. Talk to your healthcare provider about your risk for these cancers. Your healthcare provider should check your skin before and during treatment with Qinlock to look for any new skin cancers. Check your skin and tell your healthcare provider right away about any skin changes, including a:

  • new wart
  • skin sore or reddish bump that bleeds or does not heal
  • change in size or color of a mole

High blood pressure (Hypertension). High blood pressure is common with Qinlock and can be severe. Your healthcare provider should check your blood pressure regularly during treatment with Qinlock.

Heart problems. Your healthcare provider should check you for signs or symptoms of heart failure before starting Qinlock and regularly during treatment with Qinlock. Heart failure can be serious and can sometimes lead to death. Tell your healthcare provider right away if you have any of the following signs or symptoms during your treatment with Qinlock:

  • tiredness
  • shortness of breath
  • swelling of your stomach‑area (abdomen), legs or ankles
  • protruding neck veins

Risk of wound healing problems. Wounds may not heal well during treatment with Qinlock. Tell your healthcare provider if you plan to have any surgery before or during treatment with Qinlock. Your healthcare provider should tell you when to stop taking Qinlock before a planned surgery and when you may start taking Qinlock again after surgery.

Risk of sensitivity to sunlight (photosensitivity). Your skin may be sensitive to the sun or other forms of light during treatment with Qinlock. Avoid or limit exposure to direct sunlight, sunlamps, and other sources of ultraviolet radiation during treatment and for at least 1 week after stopping treatment with Qinlock. Use sunscreen and wear clothes that cover your skin if you need to be out in the sun.

The most common side effects of Qinlock include:

  • hair thinning or hair loss
  • tiredness
  • nausea
  • stomach (abdominal) pain
  • constipation
  • muscle pain
  • diarrhea
  • decreased appetite
  • vomiting

These are not all the possible side effects of Qinlock.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1‑800‑FDA‑1088.

It is not known if Qinlock is safe and effective in children.

Before taking Qinlock, tell your healthcare provider about all of your medical conditions, including if you:

  • had a type of skin problem called palmar‑plantar erythrodysesthesia syndrome
  • have high blood pressure
  • have heart problems
  • had or plan to have surgery

Tell your healthcare provider if you:

  • are pregnant or plan to become pregnant. Qinlock can harm your unborn baby.
  • or your partner becomes pregnant, or you think you may be pregnant during treatment with Qinlock.
  • are breastfeeding or plan to breastfeed. It is not known if Qinlock passes into your breast milk. Do not breastfeed during treatment with Qinlock and for 1 week after your last dose.

Females who can become pregnant:

  • Your healthcare provider will do a pregnancy test before you start treatment with Qinlock.
  • You should use effective birth control (contraception) during treatment with Qinlock and for 1 week after the last dose. Talk to your healthcare provider about birth control methods that may be right for you.

For males with female partners who can become pregnant:

  • You should use effective birth control during treatment with Qinlock and for 1 week after your last dose.

Qinlock may affect fertility in males which may affect the ability to have children. Talk to your healthcare provider if this is a concern for you.

Tell your healthcare provider about all the medicines you take, including prescription and over‑the‑counter medicines, vitamins, and herbal supplements. Qinlock and certain other medicines can affect each other causing side effects or affect how Qinlock works.

Know the medicines you take. Keep a list of them to show to your healthcare provider and pharmacist when you get a new medicine.

General information about the safe and effective use of Qinlock.

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. Do not use Qinlock for a condition for which it was not prescribed. Do not give Qinlock to other people, even if they have the same symptoms that you have. It may harm them. You can ask your pharmacist or healthcare provider for information about Qinlock that is written for health professionals.

Indication

What is Qinlock?

Qinlock is a prescription medicine used to treat adults with advanced gastrointestinal stromal tumor (GIST) who have received prior treatment with 3 or more kinase inhibitor medicines, including imatinib, for their GIST.

Please see complete Prescribing Information, including Patient Information.

Important Safety Information

Qinlock may cause serious side effects, including:

A skin problem called palmar‑plantar erythrodysesthesia syndrome. Skin problems are common and sometimes can be severe. Tell your healthcare provider right away if you develop redness, pain, blisters, bleeding, or swelling on the palms of your hands or soles of your feet, or severe rash during treatment with Qinlock.

New skin cancers. Qinlock may cause skin cancers called cutaneous squamous cell carcinoma, keratoacanthoma, or melanoma. Talk to your healthcare provider about your risk for these cancers. Your healthcare provider should check your skin before and during treatment with Qinlock to look for any new skin cancers. Check your skin and tell your healthcare provider right away about any skin changes, including a:

  • new wart
  • skin sore or reddish bump that bleeds or does not heal
  • change in size or color of a mole

High blood pressure (Hypertension). High blood pressure is common with Qinlock and can be severe. Your healthcare provider should check your blood pressure regularly during treatment with Qinlock.

Heart problems. Your healthcare provider should check you for signs or symptoms of heart failure before starting Qinlock and regularly during treatment with Qinlock. Heart failure can be serious and can sometimes lead to death. Tell your healthcare provider right away if you have any of the following signs or symptoms during your treatment with Qinlock:

  • tiredness
  • shortness of breath
  • swelling of your stomach‑area (abdomen), legs or ankles
  • protruding neck veins

Risk of wound healing problems. Wounds may not heal well during treatment with Qinlock. Tell your healthcare provider if you plan to have any surgery before or during treatment with Qinlock. Your healthcare provider should tell you when to stop taking Qinlock before a planned surgery and when you may start taking Qinlock again after surgery.

Risk of sensitivity to sunlight (photosensitivity). Your skin may be sensitive to the sun or other forms of light during treatment with Qinlock. Avoid or limit exposure to direct sunlight, sunlamps, and other sources of ultraviolet radiation during treatment and for at least 1 week after stopping treatment with Qinlock. Use sunscreen and wear clothes that cover your skin if you need to be out in the sun.

The most common side effects of Qinlock include:

  • hair thinning or hair loss
  • tiredness
  • nausea
  • stomach (abdominal) pain
  • constipation
  • muscle pain
  • diarrhea
  • decreased appetite
  • vomiting

These are not all the possible side effects of Qinlock.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1‑800‑FDA‑1088.

It is not known if Qinlock is safe and effective in children.

Before taking Qinlock, tell your healthcare provider about all of your medical conditions, including if you:

  • had a type of skin problem called palmar‑plantar erythrodysesthesia syndrome
  • have high blood pressure
  • have heart problems
  • had or plan to have surgery

Tell your healthcare provider if you:

  • are pregnant or plan to become pregnant. Qinlock can harm your unborn baby.
  • or your partner becomes pregnant, or you think you may be pregnant during treatment with Qinlock.
  • are breastfeeding or plan to breastfeed. It is not known if Qinlock passes into your breast milk. Do not breastfeed during treatment with Qinlock and for 1 week after your last dose.

Females who can become pregnant:

  • Your healthcare provider will do a pregnancy test before you start treatment with Qinlock.
  • You should use effective birth control (contraception) during treatment with Qinlock and for 1 week after the last dose. Talk to your healthcare provider about birth control methods that may be right for you.

For males with female partners who can become pregnant:

  • You should use effective birth control during treatment with Qinlock and for 1 week after your last dose.

Qinlock may affect fertility in males which may affect the ability to have children. Talk to your healthcare provider if this is a concern for you.

Tell your healthcare provider about all the medicines you take, including prescription and over‑the‑counter medicines, vitamins, and herbal supplements. Qinlock and certain other medicines can affect each other causing side effects or affect how Qinlock works.

Know the medicines you take. Keep a list of them to show to your healthcare provider and pharmacist when you get a new medicine.

General information about the safe and effective use of Qinlock.

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. Do not use Qinlock for a condition for which it was not prescribed. Do not give Qinlock to other people, even if they have the same symptoms that you have. It may harm them. You can ask your pharmacist or healthcare provider for information about Qinlock that is written for health professionals.

Indication

What is Qinlock?

Qinlock is a prescription medicine used to treat adults with advanced gastrointestinal stromal tumor (GIST) who have received prior treatment with 3 or more kinase inhibitor medicines, including imatinib, for their GIST.

Please see complete Prescribing Information, including Patient Information.